Student Profile
			  
        
                Peter Archibald
                Using clinical demand and technological solutions to accelerate the adoption of Mesenchymal Stem Cell based therapies for simultaneous indications 
                PhD Supervisor(s): David Williams 
               
          
          
               
              PhD Summary
              
                -  An EPSRC Centre for Innovative Manufacturing in Regenerative Medicine research project  in collaboration with TAP Biosystems (Royston, UK), LGC Standards (Teddington, UK) & Institute for Stem Cell Therapy & Exploration of Monogenic Diseases (I-Stem) (Paris, France)
 
                -  Comparison of manual and automated cell culture process steps- Examine the effects of Centrifugation  & Non-Centrifugation process steps upon the growth and characteristics of hMSCs, Ruler hESCs & hiPSCs
                Measurements of growth, viability, Short Tandem Repeat Profile, surface marker expression, and functionality 
                -  Perform a mock Health Technology Appraisal (HTA) of Allogeneic Islet Transplantation using current and value-based appraisal methodologies, and examine the feasibility of the reimbursement of a pluripotent derived beta-cell therapy
 
                -  Monitor future changes to the current UK reimbursement scheme
 
                -  Adapt current healthcare product appraisal methods to account for the treatment of multiple indications
 
              
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